Disturbance of intestinal permeability and its role in the development of cardiovascular complications in persons with inflammatory bowel diseases

Inflammatory bowel diseases (IBD) are one of the most complex and significant problems modern gastroenterology. The steady increase in morbidity, pathogenetic mechanisms development, presence severe extra-intestinal manifestations complications make this problem socially significant. article presents views on some aspects pathogenesis IBD. Currently, key links development progression IBD, as well associated cardiovascular state intestinal microbiota level endotoxemia. role trimethylamine N-oxide a factor early atherosclerosis patients with IBD was determined.